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  Francis X. McConville brings nearly 30 years of experience in the chemical field, including process development and scale-up, with expertise in asymmetric crystallization, biocatalytic conversion and fermentation as well as traditional chemical synthetic methods. He is perhaps best known as the author of the acclaimed Pilot Plant Real Book, a unique handbook for process development personnel, which he wrote and self-published in 2002.Mr. McConville spent 14 years as a process engineer at Sepracor, Inc. where he helped develop cost-effective processes for numerous pharmaceutical actives and intermediates. He was a key member of the technology transfer and scale-up teams for the company's collaborations in Asia, Europe and North America. He was educated at Worcester Polytechnic Institute, from which he holds Masters degrees in both Biotechnology and Chemical Engineering, as well as a Bachelor's degree in Chemistry. This varied background allows him to bring a unique and valuable mix of skills to his work. He now works as a consultant and training instructor and lives with his family in Worcester, Massachusetts. See his complete curriculum vitae. Mr. McConville is also affiliated with IMPACT Technology Consultants, Inc.  of Lincoln, Mass., an engineering firm focused on resolving technology-based issues in Pharma, Fine Chemicals and Biotech. He also teaches an industrial training course for R&D personnel entitled "Secrets of Batch Process Scale-Up" through UK-based Scientific Update. The course has been presented throughout Europe and North America and is available to be taught in-house.
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| Process Technology • Asymmetric Crystallization • Selective Biocatalysis • Fermentation • Crystallization • Product Drying |
Scale-Up/Tech Transfer • Process Optimization • Scalability Studies • Haz-Op Reviews • Economic Modelling • Start-Up/Troubleshooting | Other • cGMP for Pharma • Equipment Spec • System Design • SOP Development • Training |
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